Reason for Hirosae's Isoaltion is ERIC.
In City accydent Event clearly see that victim of accydent its Eric from UBOK, it seems Hirosae was or maybe even still is good friend of Eric, in UBOK endings Eric was hit by car, Hirosae was witness of this accydent and after she undestand its Eric its make her very sad, she thought that Eric died after that and isolate herself from the world, possibly she blame herself for this, but fortunatelly in secret and true ending of UBOK Eric is survived and wakes up in hospital room, well and live, possibly note that he found in his hospital room from Hirosae.